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Data Set Name Echocardiography of the mouse and rat heart after exposure to chronic neutrons, silicon ions, with and without the administration of aspirin as a potential countermeasure
Data Set Description Echocardiography data obtained at 400 and 800 days after the start of radiation exposure in the following groups (each in a separate tab in the datasheet):

- Male C3H mice exposed to a single dose of silicon ions and treated chronically with low-dose aspirin for 400 days after radiation
- Female Balb/C mice exposed to low-dose rate neutrons for 400 days
- Male C3H mice exposed to low-dose rate neutrons for 400 days
- Male C3H mice exposed to low-dose rate neutrons for 400 days and treated chronically with low-dose aspirin during radiation
- Male Long Evans rats exposed to low-dose rate neutrons
- Some of the heart from these mice were tested in an oxygraph and data listed in file “80NSSC17K0425 Heart mitochondria data”

Transthoracic echocardiography was performed in rats and mice under light (2%) isoflurane anesthesia using a 12 MHz sector or 15 MHz linear array transducer connected to a Phillips XD11 Ultrasound system. Short axis 2D images were used to determine left ventricular end-diastolic and end-systolic areas, fractional shortening, and wall thicknesses. No outliers identified.

Level of Processing Processed - Microsoft Excel
Data Files [Available online]
Data Collection Site(s) Investigator laboratory
Data Source Experiment
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Responsible NASA Official The NASA representative responsible for providing this information is:
Johnson Space Center LSDA Office
Project Manager: Jessica Keune