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Data Set Name Effects of Spaceflight on Bone Microarchitecture in the Axial and Appendicular Skeleton in Growing Ovariectomized Rats
Data Set Description Length, densitometry and MicroCT measurements of bones following a 14 day Spaceflight. Please see Effects of spaceflight on bone microarchitecture in the axial and appendicular skeleton in growing ovariectomized rats, doi: 10.1038/srep18671 for further analysis.

Three groups were studied: Baseline Control (BSL), Ground Control, and Spaceflight (Flight). Individual values, mean, standard deviation (SD), standard error (SE) and coefficient of variance (CV) are reported. For femur (Table 1) we report: length measured with calipers, densitometry measured by DXA and cortical and cancellous bone microarchitecture measured by microCT. The DXA measurements include total femur area, bone mineral content (BMC) and bone mineral density (BMD). MicroCT measures of total and cortical bone consist of cross sectional area, cortical area, marrow area, cortical thickness and polar moment of inertia (pMOI). Cancellous bone measurements were performed at 2 sites (metaphysis and epiphysis). Cancellous measures consist of bone volume/tissue volume (BV/TV), connectivity density, structure model index (SMI), trabecular number (Tb.N), trabecular thickness (Tb.Th) and trabecular spacing (Tb.Sp). For humerus ground controls and flight animals (BSL were not available) (Table 2) we report length, densitometry and MicroCT measurements for total, cortical and cancellous bone. For lumbar vertebrae 2 (LV2) (Table 3) we report MicroCT measures for cancellous bone for ground control and flight animals. BSL were not available. For parietal bone we used MicroCT to measure bone thickness (Table 3)

Level of Processing Processed - Microsoft Excel Spreadsheet
Data Files [Available online]
Data Collection Site(s) Investigator laboratory
Data Source Experiment
Experiments
Missions
+ Ground
Protocol/Approach
Hindlimb unloaded (HLU)
Responsible NASA Official The NASA representative responsible for providing this information is:
Johnson Space Center LSDA Office
Project Manager: Eric R. Gallagher