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EXPERIMENT INFORMATION

Trace Element Balance in Rats During Spaceflight (COS 1887-28)
Principal Investigator
Research Area:
Bone and calcium physiology
Species Studied
Scientific Name: Rattus norvegicus Species: Rat Strain: Wistar

Description
Objectives:

Little is known about the effects of space flight in an older skeleton. Limited data suggest that bone resorption is increased after five days, but no data are available about other metabolic effects. The response of a more slowly growing skeleton may be different than that of a younger animal, similar to the different responses seen in adolescents and adult humans to immobilization. This experiment was designed to investigate changes occurring in skeletal and mineral homeostasis in older, space-flown rats.


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Publications
Cann, C.E. et al.: Trace Element Balance in Rats During Spaceflight. Final Reports of the U.S. Experiments Flown on the Soviet Biosatellite Cosmos 1887. J.P. Connolly, R.E. Grindeland, and R.W. Ballard, eds., NASA TM-102254, 1990, pp. 151-155.

Keywords
Bone resorption
Bone mineralization
Osteocalcin
Calcium

Data Information
Data Availability
Archive is complete. No data sets are available for this experiment. Please Contact LSDA if you know of available data for this investigation.

Parameters
Composition, Diet, rat, Cosmos
Content, Calcium, vertebra, bone, rat, Atomic absorption spectrophotometry
Content, Calcium, vertebra, bone, rat, Microprobe, crystal sensors
Content, Osteocalcin, vertebrae, rat, Immunoassay, rat-specific
Content, Phosphorus, vertebra, bone, rat, Microprobe, crystal sensors
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Mission/Study Information
Mission Launch/Start Date Landing/End Date Duration
Cosmos 1887 09/29/1987 10/11/1987 13 days

Additional Information
Managing NASA Center
Ames Research Center (ARC)
Responsible NASA Representative
Ames Research Center LSDA Level 3
Project Manager: Helen Stewart
Institutional Support
National Aeronautics and Space Administration (NASA)
Alternate Experiment Name
C1887-16
Protocol / Approach
Hardware Items