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EXPERIMENT INFORMATION

Morphometric Studies of Atrial Granules and Hepatocytes: I. Morphometric Study of the Liver (COS 1887-15)
Principal Investigator
Research Area:
Endocrinology
Species Studied
Scientific Name: Rattus norvegicus Species: Rat Strain: Wistar

Description
Objectives:

The goal of the present study was to characterize the vacuoles, to obtain data with which to evaluate the gross and microscopic differences, and, if possible, to explain the increased liver weight of the flight group from microscopic morphometric findings. In addition to the use of general histological techniques, morphology of the hepatocyte nuclei and intracytoplasmic vacuoles was undertaken using light microscopic computer assisted image analysis.


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Publications
Kraft, L.M. et al.: Morphometric Studies of Atrial Granules and Hepatocytes: I. Morphometric Study of the Liver. Final Reports of the U.S. Experiments Flown on the Soviet Biosatellite Cosmos 1887. J.P. Connolly, R.E. Grindeland, and R.W. Ballard, eds., NASA TM-102254, 1990, pp. 279-290.

Keywords
Vacuoles
Liver
Cell nucleus
Hepatocytes

Data Information
Data Availability
Archive is complete. No data sets are available for this experiment. Please Contact LSDA if you know of available data for this investigation.

Parameters
Composition, Hepatocytes, cytoplasm, caudate lobe, liver, rat, Light microscope, measured (number)
Density, Nucleii, hepatocytes, liver, rat, Light microscopic computer assisted image analysis (calculation)
Density, Vacuoles, nucleii,, hepatocytes, liver, rat, Light microscopic computer assisted image analysis (calculation)
Morphology, Parenchyma, liver, rat, Light and electron microscopy (descriptive)
Morphology, Parenchyma, lung, rat, Light and electron microscopy (descriptive)
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Mission/Study Information
Mission Launch/Start Date Landing/End Date Duration
Cosmos 1887 09/29/1987 10/11/1987 13 days

Additional Information
Co-Investigators
Managing NASA Center
Ames Research Center (ARC)
Responsible NASA Representative
Ames Research Center LSDA Level 3
Project Manager: Helen Stewart
Institutional Support
National Aeronautics and Space Administration (NASA)
Alternate Experiment Name
C1887-17.1
Protocol / Approach
Hardware Items