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EXPERIMENT INFORMATION

Morphometric Studies of Atrial Granules and Hepatocytes: II. Atrial Granular Accumulations (COS 1887-14)
Principal Investigator
Research Area:
Endocrinology
Species Studied
Scientific Name: Rattus norvegicus Species: Rat Strain: Wistar

Description
Objectives:

Since electrolyte imbalance and fluid shifts have been experienced by humans (and animals) during space flight, it seemed appropriate to examine the atrial natriuretic factor (ANF) granulated regions in the atria of rats from the Cosmos 1887 flight, and to ascertain, by means of morphometric and stereological methods, if quantitative changes occurred in flight animals.


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Publications
Kraft, L.M. and L.C. Keil: Morphometric Studies of Atrial Granules and Hepatocytes: II. Atrial Granular Accumulations. Final Reports of the U.S. Experiments Flown on the Soviet Biosatellite Cosmos 1887. J.P. Connolly, R.E. Grindeland, and R.W. Ballard, eds., NASA TM-102254, 1990, pp. 291-296.

Keywords
Liver
Vacuoles
Cell nucleus
Myocardium
Atrial natriuretic factor (ANF)

Data Information
Data Availability
Archive is complete. No data sets are available for this experiment. Please Contact LSDA if you know of available data for this investigation.

Parameters
Density, Granules, myocardium, atria, heart, rat, Microscopy, image analysis system (number per area)
Density, volume, Granules, myocardium, atria, heart, rat, Microscopy, image analysis system (number per area)
Morphology, Myocardium, auricle, heart, rat, Light microscopy, computer assisted metrics (area, volume, density)
Morphometry, Granular regions, atria, heart, rat, Image analysis system, stereology program, volume density, mean volume, numerical density

Mission/Study Information
Mission Launch/Start Date Landing/End Date Duration
Cosmos 1887 09/29/1987 10/11/1987 13 days

Additional Information
Co-Investigators
Managing NASA Center
Ames Research Center (ARC)
Responsible NASA Representative
Ames Research Center LSDA Level 3
Project Manager: Helen Stewart
Institutional Support
National Aeronautics and Space Administration (NASA)
Alternate Experiment Name
C1887-17.2
Protocol / Approach
Hardware Items