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EXPERIMENT INFORMATION

Bed Rest Standard Measures: Plasma Volume (BRSMPV)
Research Area:
Cardiovascular physiology
Species Studied
Scientific Name: Homo sapiens Species: Human

Description
OBJECTIVES:
The objective of this test was to measure plasma volume to aid in the proper assessment of hemodynamic parameters, vascular responses, and cardiac size and function. The investigators hypothesized that plasma volume losses will be similar to those following space flight. They expected to see changes in blood volume for subjects following extended periods of bed rest.


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Publications
Cromwell, RL and Neigut, J. Lunar Analog Feasibility Study Results. 12/09/2009. Conference Paper JSC-CN-19436. NASA Johnson Space Center; Houston, TX, United States.

Platts SH, Martin DS, Stenger MB, Perez SA, Ribeiro LC, Summers R, and Meck JV. Cardiovascular Adaptations to Long-Duration Head-Down Bed Rest. Aviation, Space, and Environmental Medicine. May 2009. 80: Supplement 1, A29-A36. [pubmed.gov]

Stenger MB, Evans JM, Knapp CF, Lee SM, Phillips TR, Perez SA, Moore AD Jr, Paloski WH, and Platts SH. Artificial Gravity Training Reduces Bed Rest-Induced Cardiovascular Deconditioning. European Journal of Applied Physiology. 2012. February; 112(2):605-16 [pubmed.gov]

Keywords
Plasma volume
Carboxyhemoglobin
Hematocrit
Hemoglobins
Blood volume

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Data Information
Data Availability
Archive is complete. Data sets are not publicly available but can be requested.
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Parameters
Blood volume
Hematocrit
Hemoglobin
Plasma volume
Red blood cell volume

Mission/Study Information
Mission Launch/Start Date Landing/End Date Duration
Campaign 1 08/29/2004 11/21/2004 84 days
Campaign 11 05/11/2011 12/15/2014 3 years, 7 months, 4 days
Campaign 17 05/11/2011 02/12/2012 278 days
Campaign 19 08/15/2014 12/31/2014 138 days
Campaign 3 02/20/2005 04/14/2010 5 years, 1 month, 25 days
Campaign 5 04/30/2006 12/23/2007 1 year, 7 months
DBLS 05/03/2010 05/23/2010 Discontinued
HDT30 10/13/2009 05/13/2010 213 days
LAFS 04/13/2008 12/19/2008 250 days
LAFSP2 04/20/2009 08/27/2009 130 days
Pilot 02/05/2006 12/22/2006 320 days

Additional Information
Managing NASA Center
Johnson Space Center (JSC)
Responsible NASA Representative
Johnson Space Center LSDA Office
Project Manager: Pamela A. Bieri
Institutional Support
National Aeronautics and Space Administration (NASA)