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EXPERIMENT INFORMATION

Rodent Tissue Repair: I. Skin Repair Studies (COS 2044-43)
Principal Investigator
Research Area:
Muscle physiology
Species Studied
Scientific Name: Rattus norvegicus Species: Rat Strain: Wistar

Description
Objectives:

The aim of this experiment was to determine the effects of microgravity on the healing and repair of skin connective tissue and skeletal muscle. Two days preflight, skin and lateral head of the medial gastrocnemius, medial soleus, and fibula of hind limbs from five of the flight rats were cut and wounds sutured after surgery.


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Publications
Vailas, A.C. et al.: Adaptations of Young Adult Rat Cortical Bone to 14 Days of Spaceflight. Journal of Applied Physiology, supl., vol. 73, no. 2, 1992, pp. 4S-9S.

Vailas, A.C. et al.: Connective Tissue Studies: I. Rat Skin, Normal and Repair. Final Reports of the U.S. Experiments Flown on the Soviet Biosatellite Cosmos 2044. Vol. 2. J.P. Connolly, R.E. Grindeland, and R.W. Ballard, eds., NASA TM-108802, 1994, pp. 235-238.

Keywords
Collagen
DNA
Hematoxylin
Hydroxyproline
Immunohistochemistry
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Data Information
Data Availability
Archive is complete. No data sets are available for this experiment. Please Contact LSDA if you know of available data for this investigation.

Parameters
Activity, Healing, repair process, skin, gastrocnemius, soleus, fibula, rat, Histology and immunocytochemistry
Activity, Tissue repair assessment, skin, rat, Histology, wound markers
Content, Collagen, skin, rat, Hydroxyproline assay
Content, DNA, skin, rat
Content, Hydroxyproline, skin, rat
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Mission/Study Information
Mission Launch/Start Date Landing/End Date Duration
Cosmos 2044 09/15/1989 09/29/1989 14 days

Additional Information
Managing NASA Center
Ames Research Center (ARC)
Responsible NASA Representative
Ames Research Center LSDA Level 3
Project Manager: Helen Stewart
Institutional Support
National Aeronautics and Space Administration (NASA)
Alternate Experiment Name
C2044-13.1
Protocol / Approach
Proposal Date
6/17/1988
Proposal Source
88-OSSA-9
Hardware Items