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Effects of Long-Duration Spaceflight on Venous and Arterial Compliance in Astronauts: Bed Rest Study (BEDREST_NaVC)
Principal Investigator
Research Area:
Cardiovascular physiology
Metabolism and nutrition
Ocular physiological phenomena
Species Studied
Scientific Name: Homo sapiens Species: Human

Spaceflight Associated Neuro-ocular Syndrome (SANS) is a medical condition made up of a constellation of symptoms affecting at least 34 percent of American astronauts who have flown International Space Station (ISS) missions. SANS is defined primarily by visual acuity deficits and anatomical changes to eye structures. Exposure to head-down tilt bed rest, a well-accepted analog to induce cardiovascular adaptations similar to space flight, has not resulted in findings representative of SANS that have been observed in some astronauts participating in long-duration ISS missions. Factors other than the cephalad fluid shift observed during space flight and bed rest have been hypothesized to contribute to the development of SANS but have not been tested.

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Arterial pressure
Venous pressure

Data Information
Data Availability
Archive is complete. Data sets are not publicly available but can be requested.
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Arterial stiffness
Blood pressure
Diastolic blood pressure
Diastolic diameter
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Mission/Study Information
Mission Launch/Start Date Landing/End Date Duration
Campaign 19 08/15/2014 12/31/2014 138 days

Human Research Program (HRP) Human Research Roadmap (HRR) Information
Crew health and performance is critical to successful human exploration beyond low Earth orbit. The Human Research Program (HRP) investigates and mitigates the highest risks to human health and performance, providing essential countermeasures and technologies for human space exploration. Risks include physiological and performance effects from hazards such as radiation, altered gravity, and hostile environments, as well as unique challenges in medical support, human factors, and behavioral health support. The HRP utilizes an Integrated Research Plan (IRP) to identify the approach and research activities planned to address these risks, which are assigned to specific Elements within the program. The Human Research Roadmap is the web-based tool for communicating the IRP content.

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Additional Information
Managing NASA Center
Johnson Space Center (JSC)
Responsible NASA Representative
Johnson Space Center LSDA Office
Project Manager: Jessica Keune
Institutional Support
National Space Biomedical Research Institute (NSBRI)
Proposal Date
Proposal Source
2012 Crew Health NNJ12ZSA