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Integrated Medical Model (GRC Simulations) (IMM_GRC)
Principal Investigator
Research Area:
Clinical medicine
Species Studied
Scientific Name: Homo sapiens Species: Human

NASA Glenn Research Center (GRC) supports Integrated Medical Models (IMMs) by developing simulation based models that forecast medical event likelihood from first principle and root cause information. The specific models to be developed to inform IMM are typically assigned and prioritized by the Exploration Medical Capabilities (ExMC) Element and the science and clinical team supporting the IMM. In general this effort utilizes a modified simulation probabilistic risk analysis (Simulation PRA) approach where deterministic models are used to integrate lower level observed phenomena to assess the likelihood of higher level clinical events. Since this approach is based on PRA, it is scenario dependent and must be carefully constructed to include all critical information.

There were four primary projects in this study:

  1. Sleep Disruption medical Intervention forecasting (SDMIF) Tool
  2. Head (and Neck) injury Risk Module (HIRM)
  3. Abdominal Injury Module (AIM)
  4. Bayesian Medical Event Predictions (BMEP)

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Nelson ES, Lewandowski B, Licata A, and Myers JG. Development and validation of a predictive bone fracture risk model for astronauts. Annals of Biomedical Engineering. 2009. November; 37(11):2337-59.

Bone density
Models, biological
Risk assessment

Data Information
Data Availability
Archive is complete. Data sets are not publicly available but can be requested.
Data Sets+ Request data

Fracture incidence
Fracture risk
Fracture, femoral neck
Fracture, spinal
Fracture, wrist
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Mission/Study Information
Mission Launch/Start Date Landing/End Date Duration
Ground 05/01/2009 In Progress

Additional Information
Managing NASA Center
Johnson Space Center (JSC)
Responsible NASA Representative
Johnson Space Center LSDA Office
Project Manager: Jessica Keune
Institutional Support
National Aeronautics and Space Administration (NASA)
Proposal Date
Proposal Source
Directed Research