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EXPERIMENT INFORMATION

Human Cerebral Autoregulation during Long-duration Spaceflight (Cerebral_Autoreg)
Principal Investigator
Research Area:
Cardiovascular physiology
Species Studied
Scientific Name: Homo sapiens Species: Human

Description
OBJECTIVES:
In the previous Neurolab (STS-90) mission, a study showed that human cerebral autoregulation was preserved, and possibly even improved, by two weeks after space flight. However, the study might suffer from the small number of subjects or the special character of the mission as major limitations shared by most research in space. The specific aims of this study are to confirm reproducibility of the results from the Neurolab mission and to reveal the effects of prolonged space flight on cerebral circulation.

The main objective of the study is to determine the effects of short and long-duration space flight on cerebral blood flow autoregulation in humans by analyzing waveforms of arterial blood pressure and blood flow velocity in the middle cerebral artery recorded by transcranial Doppler (TCD).


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Keywords
Cerebral arteries
Ultrasonography
Blood flow velocity

Data Information
Data Availability
Archiving in progress. Data is not yet available for this experiment.

Parameters
Arterial blood pressure (ABP)
Cerebral autoregulation
Cerebral blood flow velocity (CBFV)

Mission/Study Information
Mission Launch/Start Date Landing/End Date Duration
Expedition 56 06/03/2018 10/04/2018 123 days
Expedition 57 10/04/2018 In progress
Expedition 58 Future mission
Expedition 59 Future mission
Expedition 60 Future mission

Additional Information
Managing NASA Center
Johnson Space Center (JSC)
Responsible NASA Representative
Johnson Space Center LSDA Office
Project Manager: Terry Hill
Institutional Support
Japan Aerospace Exploration Agency (JAXA)
Proposal Date
Proposal Source
International