EXPERIMENT INFORMATION
Human Cerebral Autoregulation during Long-duration Spaceflight (Cerebral_Autoreg)
Principal Investigator
Research Area:
Cardiovascular physiology
Species Studied
Scientific Name: Homo sapiens Species: Human
Study Type
Description
OBJECTIVES:
In the previous Neurolab (STS-90) mission, a study showed that human cerebral autoregulation was preserved, and possibly even improved, by two weeks after space flight. However, the study might suffer from the small number of subjects or the special character of the mission as major limitations shared by most research in space. The specific aims of this study are to confirm reproducibility of the results from the Neurolab mission and to reveal the effects of prolonged space flight on cerebral circulation.
In the previous Neurolab (STS-90) mission, a study showed that human cerebral autoregulation was preserved, and possibly even improved, by two weeks after space flight. However, the study might suffer from the small number of subjects or the special character of the mission as major limitations shared by most research in space. The specific aims of this study are to confirm reproducibility of the results from the Neurolab mission and to reveal the effects of prolonged space flight on cerebral circulation.
The main objective of the study is to determine the effects of short and long-duration space flight on cerebral blood flow autoregulation in humans by analyzing waveforms of arterial blood pressure and blood flow velocity in the middle cerebral artery recorded by transcranial Doppler (TCD).
Keywords
Cerebral arteries
Ultrasonography
Blood flow velocity
Data Availability
Archiving in progress. Data is not yet available for this experiment.
Parameters
Arterial blood pressure (ABP)
Cerebral autoregulation
Cerebral blood flow velocity (CBFV)
Mission/Study Information
| Mission | Launch/Start Date | Landing/End Date | Duration |
|---|---|---|---|
| Expedition 56 | 06/03/2018 | 10/04/2018 | 123 days |
| Expedition 57 | 10/04/2018 | In progress | |
| Expedition 58 | Future mission | ||
| Expedition 59 | Future mission | ||
| Expedition 60 | Future mission |
Additional Information
Co-Investigators
Managing NASA Center
Johnson Space Center (JSC)
Responsible NASA Representative
Johnson Space Center LSDA Office
Project Manager: Terry Hill
Project Manager: Terry Hill
Institutional Support
Japan Aerospace Exploration Agency (JAXA)
Proposal Date
Proposal Source
International