EXPERIMENT INFORMATION
Medical Proteome Analysis of Osteoporosis and Bone Mass-related Proteins using the Kibo Japanese Experiment Module of International Space Station (Medical_Proteomics)
Principal Investigator
Research Area:
Bone Loss Team
Species Studied
Scientific Name: Homo sapiens Species: Human
Study Type
Description
OBJECTIVES:
Investigators aim to study changes in blood proteins of astronauts before and after space flight by using the latest proteome analysis technique, and identify the causal protein of osteopenia. If protein changes due to osteopenia in space is understood, it is possible to clarify not only the cause of the osteopenia, but also the proteins that cause osteoporosis on the ground. This research will provide the knowledge in order to maintain astronauts’ health, as well as results to contribute to disease countermeasures on the ground.
Investigators aim to study changes in blood proteins of astronauts before and after space flight by using the latest proteome analysis technique, and identify the causal protein of osteopenia. If protein changes due to osteopenia in space is understood, it is possible to clarify not only the cause of the osteopenia, but also the proteins that cause osteoporosis on the ground. This research will provide the knowledge in order to maintain astronauts’ health, as well as results to contribute to disease countermeasures on the ground.
Keywords
Proteomics
Osteoporosis
Data Availability
Archiving in progress. Data is not yet available for this experiment.
Parameters
Bone alkaline phosphatase (BAP), serum
N-terminal telopeptide (NTX), serum
Procollagen I intact N-terminal propeptide (PINP), serum
Proteomics, serum
Tartrate-resistant acid phosphatase 5b (TRACP 5b), serum
Mission/Study Information
| Mission | Launch/Start Date | Landing/End Date | Duration |
|---|---|---|---|
| Expedition 55 | 02/27/2018 | 06/03/2018 | 96 days |
| Expedition 56 | 06/03/2018 | 10/04/2018 | 123 days |
| Expedition 57 | 10/04/2018 | 12/20/2018 | 77 days |
| Expedition 58 | 12/18/2018 | 03/14/2019 | 85 days |
| Expedition 59 | 03/14/2019 | 06/24/2019 | 102 days |
| Expedition 60 | 06/24/2019 | 10/03/2019 | 101 days |
Additional Information
Co-Investigators
Managing NASA Center
Johnson Space Center (JSC)
Responsible NASA Representative
Johnson Space Center LSDA Office
Project Manager: Pamela A. Bieri
Project Manager: Pamela A. Bieri
Institutional Support
Japan Aerospace Exploration Agency (JAXA)
Alternate Experiment Name
MCPT
Proposal Date
Proposal Source
International