In this investigation, the primary objective is to accomplish a comprehensive assessment of the cognitive and neurological changes that occur during long-duration spaceflight and during postflight re-adaptation to Earth’s atmosphere. The specific objectives of this investigation are to:
Behavioral measures require completion of a computerized battery of tests intended to characterize figural- and environmental-scale spatial abilities. The tests include the Santa Barbara Sense of Direction Scale (SBSOD), the Spatial Configuration Task (SCT), the Path Integration Task, the Four Mountains Task, and the Mental Rotation Task.
Neuroimaging will consist of structural and functional neuroimaging measures including anatomical MRI, diffusion tensor imaging (DTI), resting state functional MRI (rs-fMRI), task evoked functional MRI (task-fMRI), and susceptibility-weighted imaging MRI (SWI).
Neuropsychological measures will consist of a series of tests assessing a variety of cognitive functions, including executive function, attention, perception, memory, and mental imagery skills. The tests included are the Groton Maze Learning Test, the Set-Shifting Test, the Detection Test, the Identification Test, the One Card Learning Test, the Continuous Paired Associate Learning Test, the Delayed Recall Groton Maze Learning Test, the International Shopping List Test, the One-Back Test, the Two-Back Test, the Social-Emotional Cognition Test, and the Delayed Recall International Shopping List.
One preflight data collection and three postflight data collections are planned. There will be no inflight data collections.
Preflight data collection will take place between launch day minus 210 days (L-210) and L-7 and will include all three measures.
The first postflight data collection is an abbreviated data collection planned to take place between return to Earth plus 3 days (R+3) and R+5, with flexibility to extend to R+6. Only two of the tests included in the behavioral measures will be performed. They are the Spatial Configuration Test and the Path Integration Test. The neuroimaging and neuropsychological measures will not be performed.
The second postflight data collection will take place between R+14 and R+21. All three measures will be performed.
The final postflight data collection will take place between R+150 and R+210. All three measures will be performed.
Results for this investigation are unavailable. This is an international experiment. NASA does not currently have an agreement with international space partners to archive their data in the LSDA.
|Mission||Launch/Start Date||Landing/End Date||Duration|
|Expedition 55||02/27/2018||06/03/2018||96 days|
|Expedition 56||06/03/2018||10/04/2018||123 days|
|Expedition 57||10/04/2018||12/20/2018||77 days|
|Expedition 58||12/18/2018||03/14/2019||85 days|
|Expedition 59||03/14/2019||06/24/2019||102 days|
|Expedition 60||06/24/2019||10/03/2019||101 days|
|Expedition 61||10/03/2019||02/06/2020||126 days|
|Expedition 62||02/06/2020||04/17/2020||70 days|
|Expedition 63||04/17/2020||10/21/2020||187 days|
|Expedition 64||10/21/2020||04/16/2021||177 days|
|Expedition 65||04/16/2021||10/17/2021||184 days|
|Expedition 66||10/17/2021||03/30/2022||164 days|