This experiment had three specific objectives, which were expected to provide information on the changes in otolith responses due to a period in prolonged microgravity and on the re-adaptation to one-g conditions of the otolithic system. These objectives were:
1. To measure the gain, symmetry and conjugacy of the unilateral utriculo-ocular response by means of unilateral centrifugation (UC) during preflight baseline and postflight re-adaptation phases.
2. To measure the symmetry and offset of the subjective visual vertical during UC, during preflight baseline and postflight re-adaptation phases.
3. To measure vestibular evoked myogenic potentials as an indicator of saccule function during preflight baseline and postflight re-adaptation phases.
Expected results: Given that the loss of the gravitational force represents a static offloading of the otolith organs, the working hypothesis is that the dynamic OOR will be enhanced in microgravity. Immediately after return to the one-g environment therefore, a corresponding increase in the OOR gain should be observed, and over the course of the following days be observed to return to preflight basline level. This should also be the case with SVV estimation.
|Mission||Launch/Start Date||Landing/End Date||Duration|
|Expedition 18||10/12/2008||04/17/2009||187 days|
|Expedition 19||03/26/2009||10/11/2009||199 days|
|Expedition 20||05/27/2009||10/11/2009||137 days|
|Expedition 21||10/11/2009||12/01/2009||51 days|
|Expedition 22||11/30/2009||03/18/2010||109 days|
|Expedition 23||03/18/2010||06/01/2010||75 days|
|Expedition 24||06/01/2010||09/25/2010||117 days|
|Expedition 25||09/24/2010||11/25/2010||31 days|
|Expedition 26||11/26/2010||03/16/2011||111 days|
|Expedition 27||03/14/2011||05/23/2011||70 days|
|Expedition 28||05/23/2011||09/15/2011||115 days|