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Examination of the Influencing Factors of Space Flight on Autonomic Regulation of Blood Circulation, Respiration and Cardiac Contractile Function in Long Duration Space Flight (Pneumocard)
Principal Investigator
Research Area:
Cardiovascular physiology
Pulmonary physiology
Species Studied
Scientific Name: Homo sapiens Species: Human

Pneumocard is an integrated study of the adaptation of the cardiovascular system of crewmembers during a long-duration microgravity mission.

Acquiring new scientific information to refine the understanding about the mechanisms of adapting the cardiorespiratory system and the whole organism to space flight conditions. Integrated study of a cardiovascular system of astronauts in various phases of a long-duration mission in order to clarify the adaptation mechanisms and phases and determine diagnostic criteria for individual assessment of the organism adaptation to zero-gravity conditions. Study of the synchronization of heart activity and breathing factors, as well as the cardiorespiratory system control processes based on variability rate of physiological parameters. Study of interconnection between the cardiorespiratory system during a long-duration mission and tolerance of orthostatic and physical activities at the beginning of readaptation for predicting possible reactions of the crewmembers organism during the their return to ground.

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Baevsky R, Chernikova A, Funtova I, Tank J. Assessment of individual adaptation to microgravity during long term space flight based on stepwise discriminant analysis of heart rate variability parameters. Acta Astronautica. 2011;69(11-12):1148-1152.

Baevsky RM, Funtova II, Diedrich A, Pashchenko AV, Chernikova AG, Drescher J, et al. Autonomic function testing on board the ISS--update on "Pneumocard". Acta Astronautica 2007 Oct;61(7-8):672-5.

Cardiovascular physiology
Orthostatic intolerance
Heart rate
Blood pressure

Data Information
Data Availability
Archive is complete. No data sets are available for this experiment. Please Contact LSDA if you know of available data for this investigation.

Blood pressure
Heart rate
Heart rate variability

Mission/Study Information
Mission Launch/Start Date Landing/End Date Duration
Expedition 14 09/18/2006 04/21/2007 215 days
Expedition 15 04/07/2007 10/21/2007 197 days
Expedition 16 10/10/2007 04/19/2008 192 days
Expedition 17 04/08/2008 10/23/2008 198 days
Expedition 18 10/12/2008 04/17/2009 187 days
Expedition 19 03/26/2009 10/11/2009 199 days
Expedition 20 05/27/2009 10/11/2009 137 days
Expedition 21 10/11/2009 12/01/2009 51 days
Expedition 22 11/30/2009 03/18/2010 109 days
Expedition 23 03/18/2010 06/01/2010 75 days
Expedition 24 06/01/2010 09/25/2010 117 days
Expedition 27 03/14/2011 05/23/2011 70 days
Expedition 28 05/23/2011 09/15/2011 115 days

Additional Information
Managing NASA Center
Johnson Space Center (JSC)
Responsible NASA Representative
Johnson Space Center LSDA Office
Project Manager: Jessica Keune
Institutional Support
Russian Space Agency (RSA)