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Histologic Examination of Lung Tissue (COS 2044-29)
Research Area:
Pulmonary physiology
Species Studied
Scientific Name: Rattus norvegicus Species: Rat Strain: Wistar


Limited information is available regarding the effect of space flight on the respiratory system. Though animals as small as rats are not expected to undergo major cephalad fluid shifts during microgravity exposure as man does, tail-suspended rats do experience large cephalad shifts in body fluids. This study, through light and electron microscopy, compares the lung tissue of five space-flown rats to tissue from similarly maintained synchronous and tail-suspended animals.

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Elliot, A.R. et al.: Lung Morphology Study. Final Reports of the U.S. Experiments Flown on the Soviet Biosatellite Cosmos 2044. Vol. 2. J.P. Connolly, R.E. Grindeland, and R.W. Ballard, eds., NASA TM-108802, 1994, pp. 223-231.

Fluid shifts
Lung Diseases
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Data Information
Data Availability
Archive is complete. No data sets are available for this experiment. Please Contact LSDA if you know of available data for this investigation.

Count, Red blood cell, lung, rat, Clinical laboratory
Morphology, Alveolar epithelium, lung, rat, Light and electron microscopy (descriptive)
Morphology, Alveolar, edema, lung, rat, Light and electron microscopy (descriptive)
Morphology, Capillary endothelium, lung, rat, Light and electron microscopy (descriptive)
Morphology, Parenchyma, lung, rat, Light and electron microscopy (descriptive)
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Mission/Study Information
Mission Launch/Start Date Landing/End Date Duration
Cosmos 2044 09/15/1989 09/29/1989 14 days

Additional Information
Managing NASA Center
Ames Research Center (ARC)
Responsible NASA Representative
Ames Research Center LSDA Level 3
Project Manager: Helen Stewart
Institutional Support
National Aeronautics and Space Administration (NASA)
Alternate Experiment Name
Protocol / Approach
Proposal Date
Proposal Source
Hardware Items