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Biological Rhythm and Temperature Regulation: II. Metabolism (COS 2044-24)
Principal Investigator
Research Area:
Metabolism and nutrition
Species Studied
Scientific Name: Macaca mulatta Species: Monkey Strain: Rhesus


In this experiment, energy expenditure was measured in Rhesus monkeys using the doubly labeled water (2H218O) method. Determinations were made during space flight and during postflight ground control. The doubly labeled water method is the only method available for continuously measuring energy expenditure during space flight considering the severely restricted conditions of spacecraft. Therefore, this study focused on the development and use of this procedure on nonhuman primates during space flight.

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Fuller, C.A. et al.: Circadian Rhythms and Temperature Regulation During Spaceflight: II. Metabolism. Final Reports of the U.S. Experiments Flown on the Soviet Biosatellite Cosmos 2044. Vol. 2. J.P. Connolly, R.E. Grindeland, and R.W. Ballard, eds., NASA TM-108802, 1994, pp. 361-383.

Basal metabolism
Body temperature regulation
Body water
Energy metabolism
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Data Information
Data Availability
Archive is complete. No data sets are available for this experiment. Please Contact LSDA if you know of available data for this investigation.

Activity, Carbon dioxide production, primate, Doubly labeled water (2H218O) method
Activity, Protein synthesis, whole body, primate, Doubly labeled water (2H218O) method
Consumption, Diet, rat, primate, Measured water
Content, Doubly labeled water (DLW), urine, primate, Isotopic quantities
Respiration, Respiratory exchange quotient, Primate, Radioisotopic tracers (2 H, 18 O)
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Mission/Study Information
Mission Launch/Start Date Landing/End Date Duration
Cosmos 2044 09/15/1989 09/29/1989 14 days

Additional Information
Managing NASA Center
Ames Research Center (ARC)
Responsible NASA Representative
Ames Research Center LSDA Level 3
Project Manager: Martha Del Alto
Institutional Support
National Aeronautics and Space Administration (NASA)
Alternate Experiment Name
Protocol / Approach
Proposal Date
Proposal Source
Hardware Items