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A Quantitative Test of On-Orbit Exercise Countermeasures for Bone Demineralization Using a Bed Rest Analog (UWSCI)
Principal Investigator
Research Area:
Exercise physiology
Skeletal physiology
Species Studied
Scientific Name: Homo sapiens Species: Human

The specific aim of this study was to determine if individualized mechanical load replacement and supplementation during bed rest could serve as a countermeasure to losses in Bone Mineral Density (BMD), bone quality, and muscle atrophy and may demonstrate the efficacy of individualized exercise countermeasure planning.

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Cavanagh PR, Rice J, Novotny S, Hanson AM, Gopalakrishnan R, Genc KO, Englehaupt RK, Davis BL, Comstock B, Ilaslan H, Licata AA. Replacing daily loads during 84-days of bed rest: Interim Report. 18th Annual International Academy of Astronautics Humans in Space Symposium, Houston, TX, April 11-15, 2011.

Bone and bones
Bone density
Exercise test
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Photo Gallery
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Data Information
Data Availability
Archive is complete. No data sets are available for this experiment. Please Contact LSDA if you know of available data for this investigation.

Body weight
Bone density volume
Bone mineral density
Bone specific alkaline phosphatase
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Mission/Study Information
Mission Launch/Start Date Landing/End Date Duration
DBLS 05/03/2010 05/23/2010 Discontinued

Human Research Program (HRP) Human Research Roadmap (HRR) Information
Crew health and performance is critical to successful human exploration beyond low Earth orbit. The Human Research Program (HRP) investigates and mitigates the highest risks to human health and performance, providing essential countermeasures and technologies for human space exploration. Risks include physiological and performance effects from hazards such as radiation, altered gravity, and hostile environments, as well as unique challenges in medical support, human factors, and behavioral health support. The HRP utilizes an Integrated Research Plan (IRP) to identify the approach and research activities planned to address these risks, which are assigned to specific Elements within the program. The Human Research Roadmap is the web-based tool for communicating the IRP content.

The Human Research Roadmap is located at:

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Additional Information
Other Key People
Managing NASA Center
Johnson Space Center (JSC)
Responsible NASA Representative
Johnson Space Center LSDA Office
Project Manager: Jessica Keune
Institutional Support
National Aeronautics and Space Administration (NASA)
Alternate Experiment Name