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EXPERIMENT INFORMATION

Development of Countermeasures to Aid Functional Egress from the Crew Exploration Vehicle Following Long Duration Spaceflight (J08ZSA_7530)
Principal Investigator
Research Area:
Biomedical countermeasures
Neuroscience
Species Studied
Scientific Name: Homo sapiens Species: Human

Description
OBJECTIVES:
Crewmember adapted to the microgravity state may need to egress the vehicle within a few minutes for safety and operational reasons after g-transitions. During exploration class missions the interactions between a debilitated crewmember during re-adaptation to gravity and the prevailing environmental constraints imposed during gravitational transitions may lead to disruption in the ability to perform functional egress tasks. At present, no operational countermeasure has been implemented to mitigate this risk. Therefore, the overall goals of this project were to: 1) investigate performance of motor and visual tasks during simulated perturbation conditions and 2) to develop a countermeasure based on stochastic resonance to enhance sensorimotor capabilities with the aim of facilitating rapid adaptation during gravitational transitions following long-duration space flight.


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Publications
Peters BT, Mulavara AP, Cohen HS, Sangi-Haghpeykar H, and Bloomberg JJ. Dynamic visual acuity testing for screening patients with vestibular impairments. Journal of Vestibular Research. 2012. January 1; 22(2):145-51. [pubmed.gov]

Mulavara AP, Kofman IS, De Dios YE, Miller C, Peters BT, Goel R, Galvan-Garza R, and Bloomberg JJ. Using low levels of stochastic vestibular stimulation to improve locomotor stability. Frontiers in Systems Neuroscience. 2015. August 24; 9:117. pubmed.gov

Samoudi G, Jivegård M, Mulavara AP, and Bergquist F. Effects of stochastic vestibular galvanic stimulation and LDOPA on balance and motor symptoms in patients with Parkinson's disease. Brain Stimulation. 2015. May-June; 8(3):474-80. pubmed.gov

Mulavara AP, Cohen HS, Peters BT, Sangi-Haghpeykar H, and Bloomberg JJ. New analyses of the sensory organization test compared to the clinical test of sensory integration and balance in patients with benign paroxysmal positional vertigo. Laryngoscope. 2013. September; 123(9):2276-80. pubmed.gov

Goel R, Kofman I, Jeevarajan J, De Dios Y, Cohen HS, Bloomberg JJ, and Mulavara AP. Using low levels of stochastic vestibular stimulation to improve balance function. PLoS One. 2015. August 21; 10(8):e0136335. pubmed.gov

Keywords
Aging
Reflex, vestibulo-ocular
Vestibular function tests
Visual perception
Postural equilibrium

Data Information
Data Availability
Archive is complete. No data sets are available for this experiment. Please Contact LSDA if you know of available data for this investigation.

Parameters
Balance performance
Cross-planar balance performance
Dynamic visual acuity (DVA)
Eye counter roll movements
Locomotor performance
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Mission/Study Information
Mission Launch/Start Date Landing/End Date Duration
Ground 05/01/2009 In Progress

Human Research Program (HRP) Human Research Roadmap (HRR) Information
Crew health and performance is critical to successful human exploration beyond low Earth orbit. The Human Research Program (HRP) investigates and mitigates the highest risks to human health and performance, providing essential countermeasures and technologies for human space exploration. Risks include physiological and performance effects from hazards such as radiation, altered gravity, and hostile environments, as well as unique challenges in medical support, human factors, and behavioral health support. The HRP utilizes an Integrated Research Plan (IRP) to identify the approach and research activities planned to address these risks, which are assigned to specific Elements within the program. The Human Research Roadmap is the web-based tool for communicating the IRP content.

The Human Research Roadmap is located at: https://humanresearchroadmap.nasa.gov/

+ Click here for information of how this experiment is contributing to the HRP's path for risk reduction.

Additional Information
Managing NASA Center
National Space Biomedical Research Institute (NSBRI)
Responsible NASA Representative
Johnson Space Center LSDA Office
Project Manager: Jessica Keune
Institutional Support
National Space Biomedical Research Institute (NSBRI)
Alternate Experiment Name
CM Egress
NCC958SA02001
Proposal Date
10/01/2009
Proposal Source
NNJ08ZSA002N