Crewmembers will be imaged twice pre-flight (over a one-month time frame) to establish baseline data and to characterize measurement repeatability. After long-term microgravity exposure (180 days on ISS), crewmembers will be studied while maintaining supine posture as soon as possible after return to 1-G in order to quantify the acute effects of prolonged space flight. Also, pre- and post-flight, they will don a compression device so that MR images are obtained before and after 50% axial body weight load. This compression device loads the spine and simulates 50% body weight load (not including loads from muscles) on the lumbar spine in upright posture. Subsequently, crewmembers will be tested after 3 and 6 months of re-adaptation to 1-G in order to distinguish immediate and longer-term recoveries. The proposed measures represent a comprehensive set of tests that evaluate exposure severity, potential injury mechanisms, and pain generator localization.
At the conclusion of the experiment, results will be posted when data becomes available.
|Mission||Launch/Start Date||Landing/End Date||Duration|
|Expedition 33||09/16/2012||11/18/2012||63 days|
|Expedition 35||03/15/2013||05/13/2013||58 days|
|Expedition 36||05/13/2013||09/10/2013||166 days|
|Expedition 37||09/10/2013||11/10/2013||61 days|
|Expedition 39||03/10/2014||05/13/2014||64 days|
|Expedition 40||05/13/2014||09/10/2014||133 days|
|Expedition 41||09/10/2014||11/09/2014||29 days|
|Expedition 42||11/10/2014||03/11/2015||121 days|
|Expedition 43||03/11/2015||06/10/2015||91 days|
|Expedition 44||06/10/2015||09/11/2015||93 days|
|Expedition 45||09/11/2015||12/11/2015||91 days|