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EXPERIMENT INFORMATION

Surveillance of Ocular Parameters and Visual Function in Bed Rest Subjects (Ocular_Test)
Principal Investigator
Research Area:
Clinical medicine
Species Studied
Scientific Name: Homo sapiens Species: Human

Description
OBJECTIVES:
The objective of the ocular tests was to monitor subjects’ ocular health during the study. Recent evidence from astronauts returning from long-duration missions on the International Space Station (ISS) indicated vision disturbances linked to intracranial pressure affecting the optic disk and optic nerve. A Data and Safety Monitoring Board (DSMB) was constituted to monitor ocular health of the bed rest subjects.


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Publications
Taibbi G, Cromwell RL, Kapoor KG, Godley BF, and Vizzeri G. The effect of microgravity on ocular structures and visual function: a review. Survey of Ophthalmology. 2013. March-April; 58(2):155-63. [pubmed.gov]

Taibbi G, Kaplowitz K, Cromwell RL, Godley BF, Zanello SB, Vizzeri G. Effects of 30-day head-down bed rest on ocular structures and visual function in a healthy subject. Aviation, Space, and Environmental Medicine. 2013. 84:148–54. [pubmed.gov]

Taibbi G, Cromwell RL, Zanello SB, Yarbough PO, Ploutz-Snyder RJ, Godley BF, and Vizzeri G. Ocular outcomes evaluation in a 14-day head-down bed rest study. Aviation, Space, and Environmental Medicine. 2014. October; 85(10):983-92. [pubmed.gov]

Keywords
Head Down Tilt
Intraocular pressure
Retina
Retinal ganglion cells
Retinal vessels
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Data Information
Data Availability
Archive is complete. Data sets are not publicly available but can be requested.
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Parameters
Color vision
Cycloplegic refraction, axis
Cycloplegic refraction, cylindar
Cycloplegic refraction, sphere
Ganglion cell complex thickness, inferior sector
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Mission/Study Information
Mission Launch/Start Date Landing/End Date Duration
Campaign 11 05/11/2011 12/15/2014 3 years, 7 months, 4 days
Campaign 17 05/11/2011 02/12/2012 278 days
HDT30 10/13/2009 05/13/2010 213 days
iRATS14 11/09/2010 04/27/2011 160 days

Additional Information
Co-Investigators
Managing NASA Center
Johnson Space Center (JSC)
Responsible NASA Representative
Institutional Support
National Aeronautics and Space Administration (NASA)