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EXPERIMENT INFORMATION

Spaceflight Standard Measures: Cellular Profile (SSM_Cell_Profile)
Principal Investigator
Research Area:
Immunology
Species Studied
Scientific Name: Homo sapiens Species: Human

Description
OBJECTIVES:

The Cellular Profile Test Battery is one of nine Spaceflight Standard Measures conducted on International Space Station (ISS) crewmembers. Spaceflight Standard Measures are a set of core measurements, representative of many of the risks experienced by astronauts before, during, and after spaceflight. The purpose of this project is to populate a repository with data that enables high-level monitoring of countermeasure effectiveness and meaningful interpretation of health and performance outcomes. These standard measures will support future, hypothesis-driven research that enables planetary missions by providing an optimized minimal set of measures captured from all ISS crewmembers until the end of the ISS program. These measures will be available to other studies under data sharing agreements as well as undergo analysis for trends in the astronaut population.

The Cellular Profile battery of tests uses small volumes of ambient blood and liquid saliva samples. These samples encompass both innate immunity (nonspecific defense mechanisms that come into play immediately or within hours of an antigen’s appearance in the body) and adaptive immunity (antigen-specific responses that acquire after prior exposure and recruit within hours or days of re- exposure).



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Keywords
Blood
Saliva
Immunology
Immunity, cellular
Blood chemical analysis

Parameters
B cells (CD19+)
CCL5/RANTES
Complete blood count/white blood cells
Cytomegalovirus DNA concentration
Epstein-barr virus DNA concentration
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Mission/Study Information
Mission Launch/Start Date Landing/End Date Duration
Expedition 57 10/04/2018 12/20/2018 77 days
Expedition 58 12/18/2018 03/14/2019 85 days
Expedition 59 03/14/2019 06/24/2019 102 days
Expedition 60 06/24/2019 10/03/2019 101 days
Expedition 61 10/03/2019 02/06/2020 126 days

Additional Information
Managing NASA Center
Johnson Space Center (JSC)
Responsible NASA Representative
Institutional Support
National Aeronautics and Space Administration (NASA)
Alternate Experiment Name
Standard_Measures
Proposal Date
Proposal Source