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EXPERIMENT INFORMATION

Effects of Cosmic Particle Radiation on the Calvarium, Brain, and Meninges (A17-1.2)
Principal Investigator
Research Area:
Radiation biology
Species Studied
Scientific Name: Perognathus longimembris Species: Mouse, Pocket

Description
Objectives:

The stopping point region of a cosmic ray particle, the Bragg peak, has the greatest potential for injury of the brain or other tissue because it is here that the particle's LET reaches a maximum. Because an acute inflammatory reaction was observed in two monkeys within a few days after balloon flights, the decision was made to process the mice as soon as they were recovered. It was realized, however, that a considerable proportion of the acute inflammatory cells would disappear, if evoked earlier in the mission; the lifetime of these cells in tissue is no more than five days.


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Publications
Bailey, O.T. et al.: The Effects of Cosmic Particle Radiation on Pocket Mice Aboard Apollo XVII: Preflight Studies on Tolerance of Pocket Mice to Oxygen and Heat: Part IV. Observations on the Brain. Aviation, Space, and Environmental Medicine, vol. 46, no. 4, sec. II, 1975, pp. 527-528.

Cruty, M.R. et al.: The Effects of Cosmic Particle Radiation on Pocket Mice Aboard Apollo XVII: VII. Cosmic Ray Particle Dosimetry and Trajectory Tracing. Aviation, Space, and Environmental Medicine, vol. 46, no. 4, sec. II, 1975, pp. 537-552.

Haymaker, W. et al.: The Effects of Cosmic Particle Radiation on Pocket Mice Aboard Apollo XVII: XII. Results of Examination of the Calvarium, Brain and Meninges. Aviation, Space, and Environmental Medicine, vol. 46, no. 4, sec. II, 1975, pp. 613-623.

Keywords
Brain
Cosmic radiation
Linear energy transfer (LET)
Meninges
Mitosis
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Data Information
Data Availability
Archive is complete. No data sets are available for this experiment. Please Contact LSDA if you know of available data for this investigation.

Mission/Study Information
Mission Launch/Start Date Landing/End Date Duration
Apollo 17 12/07/1972 12/19/1972 12 days

Additional Information
Managing NASA Center
Ames Research Center (ARC)
Responsible NASA Representative
Ames Research Center LSDA Level 3
Project Manager: Martha Del Alto
Institutional Support
National Aeronautics and Space Administration (NASA)
Alternate Experiment Name
M121
Protocol / Approach
Trajectory control