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EXPERIMENT INFORMATION

Census of Osteoblast Precursor Cells in Periodontal Ligament (PDL) of Spacelab-3 Rats (SL3 BSP16)
Principal Investigator
Research Area:
Skeletal physiology
Species Studied
Scientific Name: Rattus norvegicus Species: Rat Strain: Sprague-Dawley

Description
Objectives:

This experiment was to examine space flight effects in the non-weightbearing bone of the rat periodontal ligament. The objective is to determine the relative influence of weightlessness on cell census of an osteogenic tissue. Previous flight data have documented a compromise in preosteoblasts, but the present study was the first opportunity to evaluate postflight recovery of osteoblast differentiation.


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Publications
Roberts WE, et al. Nuclear Morphometric Analysis of Osteoblast Precursor Cells in Periodontal Ligament, SL-3 rats. American Journal of Physiology 1987; 252:R247-51.

Roberts WE, Fielder PJ, Rosenoer LML, Maese AC, Gonsalves MR. Census of Osteoblast Precursor Cells in Periodontal Ligament (PDL) of Spacelab-3 rats. Abstract 83.3. 36th Annual Fall Meeting of the American Physiological Society; 1985 Oct 13-18; Buffalo (NY) Physiologist 1985; 28(4):376.

Keywords
Periodontal ligament (PDL)
Osteoblasts
Osteogenesis
Bone and bones
Bone mineralization

Data Information
Data Availability
Archive is complete. No data sets are available for this experiment. Please Contact LSDA if you know of available data for this investigation.

Parameters
Count, Osteoblast precursor cell, bone, periodontal ligament (PDL), rat, Microscopy

Mission/Study Information
Mission Launch/Start Date Landing/End Date Duration
STS-51B 04/29/1985 05/06/1985 7 days

Additional Information
Managing NASA Center
Ames Research Center (ARC)
Responsible NASA Representative
Ames Research Center LSDA Level 3
Project Manager: Sylvain Costes
Institutional Support
National Aeronautics and Space Administration (NASA)
Protocol / Approach
Simulated flight control
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Links