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EXPERIMENT INFORMATION

Homeostasis and Biological Rhythms in the Rat During Spaceflight (SL3 BSP28)
Principal Investigator
Research Area:
Chronobiology
Species Studied
Scientific Name: Rattus norvegicus Species: Rat Strain: Sprague-Dawley

Description
Objectives:

Homeostatic regulation of various physiological and behavioral systems may be altered as a function of the ambient gravitational environment of the organism. Changes in homeostasis have been observed in these and other systems as a result of chronic exposure to a hyperdynamic environment induced by centrifugation. Life science research capabilities are now being extended into the realm of the hypodynamic environment by research capabilities aboard spacecraft. This study examined the regulation of body temperature and heart rate in rats with biotelemetry implants.


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Publications
Fuller CA, Edger DM. Homeostasis and Biological Rhythms in the Rat During Spaceflight. Abstract 83.10. 36th Annual Fall Meeting of the American Physiological Society; 1985 Oct 13-18; Buffalo(NY): 377.

Fuller CA. Homeostasis and Biological Rhythms in the Rat During Spaceflight. Abstract S-199. Proceedings of the Seventh Annual Meeting on the IUPS Commission on Gravitational Physiology; 1985 Oct 13-18; Niagara Falls(NY).

Fuller CA. Homeostasis and Biological Rhythms in the Rat During Spaceflight. Physiologist 1985; 28(6 Suppl): S199-200.

Ishihama LM, et al. Temperature regulation in rats exposed to a 2 G field. Physiologist 1989; 32 Suppl: S61-2.

Murakami D, et al. Effects of Gravity on the Circadian Period in Rats. Physiologist 1991; 34 Suppl: S147-8.

Keywords
Homeostasis
Body temperature
Heart rate
Circadian rhythm

Data Information
Data Availability
Archive is complete. No data sets are available for this experiment. Please Contact LSDA if you know of available data for this investigation.

Parameters
Activity, Heart rate, rat, Implanted transmitter, continuous EKG, rate algorithm
Temperature, Body, rat, Biotelemetry implant, computer
Temperature, Body, rat, Implant, biotelemetry system
Temperature, RAHF data, SL-3, (quads 1-4, TEU air in/out, TEU coolant in/out), Recorder, downlink (1/sec)

Mission/Study Information
Mission Launch/Start Date Landing/End Date Duration
STS-51B 04/29/1985 05/06/1985 7 days

Additional Information
Managing NASA Center
Ames Research Center (ARC)
Responsible NASA Representative
Ames Research Center LSDA Level 3
Project Manager: Martha Del Alto
Institutional Support
National Aeronautics and Space Administration (NASA)
Protocol / Approach
Simulated flight control
Similar Experiments or Analyses
Links