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Ultrastructure and Histochemistry of Vestibular Structures and Vegatative Nuclei of the Brain (SLS2 BSP2)
Principal Investigator
Research Area:
Species Studied
Scientific Name: Rattus norvegicus Species: Rat Strain: Sprague-Dawley


One goal of spaceflight is to determine the neuronal mechanisms by which an organism adapts to microgravity in spaceflight. One structure that has shown changes in previous spaceflights is the cerebral cortex. However, in all previous studies, subjects had been exposed to reentry stresses, increasing the proprioceptive impulses to the brain. SLS-2 offered the first opportunity to examine the somatosensory and visual cortex of rats exposed to microgravity with out reentry effects.

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Fidelina OV, Corbatyuk OS, Krasnov IB, Akmayev IG: Reactions of the hypothalamic paraventricular nucleus and vagus nerve dorsalis nucleus in the rats exposed to changed gravitational environment [in Russian]. Probl. Endocrin., vol. 41(6), 1995, pp. 35-38.

Krasnov IB, Fidelina OV, Gorbatiuk OS, Vikhreva OV. Repeated exposure in hypergravity: morphology of locus coeruleus, hypothalamic paraventricular nucleus and vagal nerve dorsal nucleus in rats. Aviakosm Ekolog Med. 2000;34(3):21-7

Sergutina AV, Gershtein LM, D'Amelio FD, Donton N, Krasnov IB: Some cytochemical features of the motor system of the rat brain after spaceflight. Biull Eksp Biol Med, vol. 119(3) , Mar 1995, pp. 288-290.


Activity, motor, Rat, Microgravity, SLS-2 (counts)

Mission/Study Information
Mission Launch/Start Date Landing/End Date Duration
STS-58 10/18/1993 11/01/1993 14 days

Additional Information
Managing NASA Center
Ames Research Center (ARC)
Responsible NASA Representative
Ames Research Center LSDA Level 3
Project Manager: Martha Del Alto
Institutional Support
Russian Space Agency (RSA)
Alternate Experiment Name
Protocol / Approach
Simulated cage
Vivarium control
Proposal Date
Proposal Source