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EXPERIMENT INFORMATION

Results of Pulmonary Function Tests (ASTP012)
Research Area:
Pulmonary physiology
Species Studied
Scientific Name: Homo sapiens Species: Human

Description
OBJECTIVES:
Pulmonary function has been studied in detail following exposure to hypoxic and hyperoxic environments at normal gravity, but few studies have dealt with normoxic environments at zero gravity. Previous space flight history has shown no major changes in pulmonary function when evaluated postflight. During the first and second Skylab missions only a functional screening test on vital capacity was performed. Due to substantial decreases in cardiac output following these two missions, a more thorough pulmonary function screening effort was undertaken for Skylab 4 and the Apollo-Soyuz Test Project (ASTP). The objectives of this study were to document changes in pulmonary physiology and postflight adaptability and to determine the effect of body fluid redistribution on lung mechanics.


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Publications
Apollo-Soyuz Test Project: ASTP reference paper on USA and USSR medical requirements. 1975:71p.

DeJournette RL. Rocket propellant inhalation in the Apollo-Soyuz astronauts. Radiology 1977; 125:21.24.[pubmed.gov]

Nicogossian AE, editor. Results of pulmonary function tests. Apollo-Soyuz Test Project Biomedical Report. JSC-10985, 1976:28.

Nicogossian AE, Sawin CF, Bartelloni PJ. Results from pulmonary function tests. Apollo-Soyuz Test Project, Medical Report. NASA SP-411, 1977:25-28. [NTRS]

Rummel, JA (Ed.). BIOSPEX: Biological Space Experiments: A Summary of Life Sciences Experiments Carried on U.S. Spacecraft. JSC-13979, 1978:1-114.

Sawin CF, Nicogossian AE, Rummel JA, Michel EL. Pulmonary function evaluation during the Skylab and Apollo-Soyuz missions. Aviat Space Environ Med 1976; 47:168-172.[pubmed.gov]

Keywords
Pulmonary ventilation
Lung volume measurements
Respiration
Respiratory Function Tests
Respiratory Mechanics

Data Information
Data Availability
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Parameters
Alveolar Plateau
Alveolar volume (V<sub>A</sub>)
CC/TLC ratio
Closing capacity (CC)
Closing volume (CV)
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Mission/Study Information
Mission Launch/Start Date Landing/End Date Duration
ASTP 07/15/1975 07/24/1975 9 days, 7.5 hours

Additional Information
Managing NASA Center
Johnson Space Center (JSC)
Responsible NASA Representative
Johnson Space Center LSDA Office
Project Manager: Eric Gallagher
Institutional Support
National Aeronautics and Space Administration (NASA)
Hardware Items