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EXPERIMENT INFORMATION

Histological Studies on the Tibial Bone of Rats in the 1975 Cosmos 782 Flight: II. Micrographic Study of the Cortical Bone (COS 782-15)
Principal Investigator
Research Area:
Bone and calcium physiology
Species Studied
Scientific Name: Rattus norvegicus Species: Rat Strain: Wistar

Description
Objectives:

Conceivably, a decrease in the mineral content of a bone (as in hypogravity), could result from a shift in the balance of internal remodeling, in which a smaller proportion of osteons would be of the older, high mineral density types, and a larger proportion of the recently formed and less mineralized type. Based on this hypothesis, a study of rat cortical bone has been made by microradiography, on sample tibia from rats subjected to prolonged weightlessness.


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Publications
Asling, C.W.: Histological Studies on the Tibial Bone of Rats in the 1975 Cosmos 782 Flight: II. Microradiographic Study of Cortical Bone: Final Reports of U.S. Experiments Flown on the Soviet Satellite Cosmos 782. S.N. Rosenzweig and K.A. Souza, eds., NASA TM-78525, 1978, pp. 291-307.

Keywords
Bone density
Tibia
Bone remodeling
Microradiography

Data Information
Data Availability
Archive is complete. No data sets are available for this experiment. Please Contact LSDA if you know of available data for this investigation.

Parameters
Bone mineralization: tibia,Morphometry, Collagen fibrils, tibia, bone, rat, Microscopy, digitizing tablet
Bone porosity: tibia
Bone remodeling: tibia
Density, Tibia, bone, rat, Microradiography, microscopy, image analysis (optical density)
Density, Tibia, femur, bone, quail, Microscopy, image analysis (comparative)
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Mission/Study Information
Mission Launch/Start Date Landing/End Date Duration
Cosmos 782 11/25/1975 12/15/1975 20 days

Additional Information
Managing NASA Center
Ames Research Center (ARC)
Responsible NASA Representative
Ames Research Center LSDA Level 3
Project Manager: Helen Stewart
Institutional Support
National Aeronautics and Space Administration (NASA)
Alternate Experiment Name
C782-4.2
Protocol / Approach
Hardware Items