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Ophthalmoscopy (DSO 414)
Principal Investigator
Research Area:
Cardiovascular physiology
Clinical medicine
Species Studied
Scientific Name: Homo sapiens Species: Human

Symptoms of space motion sickness may be due in part to elevation of intracranial pressure resulting from fluid shifts occurring early in flight. An increase in intracranial pressure is first manifested clinically in the retina, as engorgement of veins in the central part of the retina and disappearance of their normal pulsations. The objective of this experiment was to assess intracranial pressure indirectly by observing the diameter and pulsation of retinal vessels.

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Thornton WE, Moore T, Pool S. Space motion sickness: characterization and etiology. In: Bungo MW, Bagian TM, Bowman MA, Levitan BM, editors. Results of the life sciences DSOs conducted aboard the Space Shuttle 1981-1986. Houston: Space Biomedical Research Institute, Johnson Space Center, 1987:159-70.

Thornton WE, Moore TP, Pool SL, Vanderploeg J. Clinical characterization and etiology of space motion sickness. Aviat Space Environ Med 1987, 58(9, Suppl.):A1-A8.[]

Fluid shifts
Intracranial pressure
Isotope labeling
Retinal vein
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Data Information
Data Availability
Archive is complete. No data sets are available for this experiment. Please Contact LSDA if you know of available data for this investigation.

Retinal blood vessels, diameter
Retinal blood vessels, pulsation

Mission/Study Information
Mission Launch/Start Date Landing/End Date Duration
STS-7 06/18/1983 06/24/1983 6 days
STS-8 08/30/1983 09/05/1983 6 days

Additional Information
Managing NASA Center
Johnson Space Center (JSC)
Responsible NASA Representative
Johnson Space Center LSDA Office
Project Manager: Pamela A. Bieri
Institutional Support
National Aeronautics and Space Administration (NASA)
Protocol / Approach