EXPERIMENT INFORMATION
Noninvasive Estimation of Central Venous Pressure During Space Flight (DSO 462)
Principal Investigator
Research Area:
Cardiovascular physiology
Renal, fluid and electrolyte physiology
Species Studied
Scientific Name: Homo sapiens Species: Human
Study Type
Description
OBJECTIVES:
Evidence suggests that cephalad fluid shifts during weightlessness stimulate arterial and cardiopulmonary baroreceptors, leading to cardiovascular readaptation syndrome. Central venous pressure (CVP) is one variable used to monitor fluid shifts. A noninvasive Doppler technique was used to document CVP during weightlessness.
Evidence suggests that cephalad fluid shifts during weightlessness stimulate arterial and cardiopulmonary baroreceptors, leading to cardiovascular readaptation syndrome. Central venous pressure (CVP) is one variable used to monitor fluid shifts. A noninvasive Doppler technique was used to document CVP during weightlessness.
Publications
Charles JB, Bennett BS. DSO 462: Noninvasive estimation of central venous pressure during space flight. In: Results of life sciences DSOs conducted aboard the Shuttle 1991-1993. Houston: NASA Johnson Space Center, 1994:21-6.
Charles JB, Bungo MW. Noninvasive estimation of central venous pressure using a compact doppler ultrasound system. In: Bungo MW, Bagian TM, Bowman MA, Levitan BM, editors. Results of the life sciences DSOs conducted aboard the Space Shuttle 1981-1986. Houston: Space Biomedical Research Institute, NASA Johnson Space Center, 1987:69-71.
Keywords
Central venous pressure
Facial bones
Fluid shifts
Photo Gallery
Data Availability
Archive is complete. All data sets are on the Web site.
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Parameters
Central venous pressure
Mission/Study Information
| Mission | Launch/Start Date | Landing/End Date | Duration |
|---|---|---|---|
| STS-29 | 03/13/1989 | 03/18/1989 | 5 days |
| STS-30 | 05/04/1989 | 05/08/1989 | 4 days |
| STS-31 | 04/24/1990 | 04/29/1990 | 5 days |
| STS-33 | 11/22/1989 | 11/27/1989 | 5 days |
| STS-51B | 04/29/1985 | 05/06/1985 | 7 days |
| STS-51C | 01/24/1985 | 01/27/1985 | 3 days |
| STS-61C | 01/12/1986 | 01/18/1986 | 6 days |
Additional Information
Co-Investigators
Managing NASA Center
Johnson Space Center (JSC)
Responsible NASA Representative
Johnson Space Center LSDA Office
Project Manager: Pamela A. Bieri
Project Manager: Pamela A. Bieri
Institutional Support
National Aeronautics and Space Administration (NASA)