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Noninvasive Estimation of Central Venous Pressure During Space Flight (DSO 462)
Principal Investigator
Research Area:
Cardiovascular physiology
Renal, fluid and electrolyte physiology
Species Studied
Scientific Name: Homo sapiens Species: Human

Evidence suggests that cephalad fluid shifts during weightlessness stimulate arterial and cardiopulmonary baroreceptors, leading to cardiovascular readaptation syndrome. Central venous pressure (CVP) is one variable used to monitor fluid shifts. A noninvasive Doppler technique was used to document CVP during weightlessness.

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Charles JB, Bennett BS. DSO 462: Noninvasive estimation of central venous pressure during space flight. In: Results of life sciences DSOs conducted aboard the Shuttle 1991-1993. Houston: NASA Johnson Space Center, 1994:21-6.

Charles JB, Bungo MW. Noninvasive estimation of central venous pressure using a compact doppler ultrasound system. In: Bungo MW, Bagian TM, Bowman MA, Levitan BM, editors. Results of the life sciences DSOs conducted aboard the Space Shuttle 1981-1986. Houston: Space Biomedical Research Institute, NASA Johnson Space Center, 1987:69-71.

Central venous pressure
Facial bones
Fluid shifts

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Data Information
Data Availability
Archive is complete. All data sets are on the Web site.
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Central venous pressure

Mission/Study Information
Mission Launch/Start Date Landing/End Date Duration
STS-29 03/13/1989 03/18/1989 5 days
STS-30 05/04/1989 05/08/1989 4 days
STS-31 04/24/1990 04/29/1990 5 days
STS-33 11/22/1989 11/27/1989 5 days
STS-51B 04/29/1985 05/06/1985 7 days
STS-51C 01/24/1985 01/27/1985 3 days
STS-61C 01/12/1986 01/18/1986 6 days

Additional Information
Managing NASA Center
Johnson Space Center (JSC)
Responsible NASA Representative
Johnson Space Center LSDA Office
Project Manager: Jessica Keune
Institutional Support
National Aeronautics and Space Administration (NASA)