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EXPERIMENT INFORMATION

Quantitative Analysis of Selected Bone Parameters (COS 1129-9)
Principal Investigator
Research Area:
Bone and calcium physiology
Species Studied
Scientific Name: Rattus norvegicus Species: Rat Strain: Wistar

Description
Objectives:

According to previous space flight research, differential effects are noted not only between weight bearing and non-weight bearing bones, but also are seen within different regions of the same bone. Therefore, one of the objectives of this study was to determine growth at the periosteum in different regions both in weight bearing (tibia) and non-weight bearing (rib) bones. Following both Cosmos 782 and 936, an arrest line was found in all flight rats and was both more distinct and more extensive than in controls. Another objective of this study was to obtain more precise measurements and further define this arrest line.


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Publications
Wronski, T.J. and E.R. Morey-Holton: Effect of Spaceflight on Periosteal Bone Formation in Rats. American Journal of Physiology, vol. 244, 1983, pp. R305-R309.

Wronski, T.J. and E.R. Morey: Alterations in Calcium Homeostasis and Bone During Actual and Simulated Spaceflight. Medicine and Science in Sports and Exercise, vol. 15, no. 5, 1983, pp. 410-414.

Wronski, T.J. et al.: Cosmos 1129: Spaceflight and Bone Changes. Physiologist, supl., vol. 23, 1980, pp. S79-S82.

Wronski, T.J. et al.: Quantitative Analysis of Selected Bone Parameters. Final Reports of U.S. Rat Experiments Flown on the Soviet Satellite Cosmos 1129. M.R. Heinrich and K.A. Souza, eds., NASA TM-81289, 1981, pp. 101-125.

Keywords
Bone and bones
Bone marrow
Bone mineralization
Cross-sectional area (CSA)
Diaphyses
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Data Information
Data Availability
Archive is complete. No data sets are available for this experiment. Please Contact LSDA if you know of available data for this investigation.

Parameters
Area, cross section, Humerus, bone, rat
Area, cross section, Tibia, rat
Bone mineralization: humerus
Bone mineralization: tibia,Morphometry, Collagen fibrils, tibia, bone, rat, Microscopy, digitizing tablet
Content, Fat, in bone marrow, tibia, proximal metaphysis, rat, Merz grid
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Mission/Study Information
Mission Launch/Start Date Landing/End Date Duration
Cosmos 1129 09/25/1979 10/14/1979 19 days

Additional Information
Managing NASA Center
Ames Research Center (ARC)
Responsible NASA Representative
Ames Research Center LSDA Level 3
Project Manager: Helen Stewart
Institutional Support
National Aeronautics and Space Administration (NASA)
Alternate Experiment Name
C1129-3.1
Protocol / Approach
Hardware Items