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EXPERIMENT INFORMATION

Single Muscle Function and EMG Analysis Associated with Microgravity Conditions (CNES F-09 1_2)
Research Area:
Muscle physiology
Species Studied
Scientific Name: Macaca mulatta Species: Monkey Strain: Rhesus

Description
Objectives:

Atrophy of some lower limb muscles, especially the antigravity muscles, has been observed in animals exposed to microgravity. Few studies have been done on the effects of microgravity on the upper limbs. Primates appear to be a good model for examining muscle contractile and biochemical properties, and making EMG recordings. This experiment will examine the effects of microgravity on the slow-type muscle of the triceps and the fast-type muscle of the biceps.


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Publications
Canu M.H. et al.: Electromyographic Activity in the Rhesus Monkey Forelimb Muscles During a Goal Directed Movement and Locomotion before, during and after Spaceflight. J Gravit Physiol. 2003 Dec;10(2):19-28

Kischel, P. et al.: Plasticity of Monkey Triceps Muscle Fibers in Microgravity Conditions. Journal of Applied Physiology, vol. 90(5), May 2001, pp. 1825-1832.

Mayet-Sornay M.H. et al.: Structural Changes in Arm Muscles After Microgravity. Journal of Gravitational Physiology, vol. 7(1), Jan 2000, pp. S43-S44.

Mounier, Y. et al.: Effect of Spaceflight on Single Fiber Function of Triceps and Biceps Muscles in Rhesus Monkeys. Journal of Gravitational Physiology, vol. 7(1), Jan 2000, pp. S51-S52.

Data Information
Data Availability
Archive is complete. No data sets are available for this experiment. Please Contact LSDA if you know of available data for this investigation.

Parameters
Maximum tension: muscle
Myosin heavy chain (MHC) isoform expression: muscle
Properties, type, Fiber, biceps, triceps medialis, muscle, primate, Microscopy
Response, Muscle, to calcium, biceps, triceps medialis, primate, Functional Ca activation characteristics (T/pCa curves)

Mission/Study Information
Mission Launch/Start Date Landing/End Date Duration
Bion 11 12/24/1996 01/07/1997 13.5 days

Additional Information
Managing NASA Center
Ames Research Center (ARC)
Responsible NASA Representative
Ames Research Center LSDA Level 3
Project Manager: Martha Del Alto
Institutional Support
National Aeronautics and Space Administration (NASA)
Alternate Experiment Name
B11-14
Protocol / Approach
Proposal Date
6/24/1988
Proposal Source
88-OSSA-8
Hardware Items