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EXPERIMENT INFORMATION

Cardiovascular Results from a Rhesus Monkey Flown Aboard the Cosmos 1514 Spaceflight, and Ground-Based Controls (COS 1514-3)
Principal Investigator
Research Area:
Cardiovascular physiology
Species Studied
Scientific Name: Macaca mulatta Species: Monkey Strain: Rhesus

Description
Objectives:

This flight experiment was designed to determine whether blood pressure and flow relationships to the head change with weightlessness. The objectives of this experiment were: 1) to develop a conscious rhesus monkey model to record carotid pressure and flow in a nonstressed animal; 2) to determine the effects of weightlessness on pressure-flow relationships to the head; and 3) to correlate cardiovascular findings with other simultaneously recorded physiologic information before, during, and after the flight.


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Publications
Korolkov, V.I. et al.: Circulation in Primates Exposed to Microgravity Aboard the Cosmos Biosatellites. Physiologist, supl., vol. 35, no. 1, 1992, pp. S245-S247.

Sandler, H. et al.: Cardiovascular Results from a Rhesus Monkey Flown Aboard the Cosmos 1514 Spaceflight, and Ground-Based Controls. Final Reports of U.S. Monkey and Rat Experiments Flown on the Soviet Satellite Cosmos 1514. R.C. Mains and E.W. Gomersall, eds., NASA TM-88223, 1986, pp. 103-127.

Sandler, H.: Cardiovascular Results from a Rhesus Monkey Flown Aboard the Cosmos 1514 Spaceflight. Aviation, Space, and Environmental Medicine, vol. 58, no. 6, 1987, pp. 529-536.

Keywords
Blood pressure
Carotid artery, common
Heart rate
Cardiovascular physiology

Data Information
Data Availability
Archive is complete. No data sets are available for this experiment. Please Contact LSDA if you know of available data for this investigation.

Parameters
Activity, Electrocardiogram (ECG), primate, Hard wire, downlink
Activity, Heart rate, primate, EKG hard wire implants, recording
Activity, Heart rate, rat, Implanted transmitter, continuous EKG, rate algorithm
Flow, blood, Carotid artery, primate, Flow transducer, cylindrical probe (CPF Cuff)
Flow, blood, Vascular resistance, carotid artery, primate, Flow transducer, cylindrical probe (CPF Cuff)
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Mission/Study Information
Mission Launch/Start Date Landing/End Date Duration
Cosmos 1514 12/14/1983 12/19/1983 5 days

Additional Information
Managing NASA Center
Ames Research Center (ARC)
Responsible NASA Representative
Ames Research Center LSDA Level 3
Project Manager: Helen Stewart
Institutional Support
National Aeronautics and Space Administration (NASA)
Alternate Experiment Name
C1514-1
Protocol / Approach