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EXPERIMENT INFORMATION

Calcium Metabolism and Correlated Endocrine Measurements in Primates (COS 1514-5)
Principal Investigator
Research Area:
Bone and calcium physiology
Renal, fluid and electrolyte physiology
Species Studied
Scientific Name: Macaca mulatta Species: Monkey Strain: Rhesus

Description
Objectives:

The problem of calcium loss from the body during space flight had been long recognized; however, little is known about the initiating mechanism of this loss. Two hypotheses have been suggested in explanation: 1) a primary increase in bone resorption due to decreased mechanical stress on the bone or 2) a primary renal calcium leak. This experiment was to measure the initial responses of the calcium homeostatic system in nonhuman primates subjected to the space flight environment.


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Publications
Cann, C.E. et al.: Calcium Metabolism and Correlated Endocrine Measurements in Primates. Final Reports of U.S. Monkey and Rat Experiments Flown on the Soviet Satellite Cosmos 1514. R.C. Mains and E.W. Gomersall, eds., NASA TM-88223, 1986, pp. 129-144.

Cann, C.E. et al.: Regulation of Calcium Metabolism in Hypodynamic Monkeys. Final Report, NASA Contract NCA2-OR745-804, October 1978.

Keywords
Calcium
Bone and bones
Bone resorption
Radius
Tibia

Data Information
Data Availability
Archive is complete. No data sets are available for this experiment. Please Contact LSDA if you know of available data for this investigation.

Parameters
Composition, Diet, primate, Shuttle
Consumption, Diet, rat, primate, Measured food
Consumption, Diet, rat, primate, Measured water
Content, Calcium, in urine, primate, Clinical chemistry
Content, Creatine, in urine, primate: Biochemistry
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Mission/Study Information
Mission Launch/Start Date Landing/End Date Duration
Cosmos 1514 12/14/1983 12/19/1983 5 days

Additional Information
Managing NASA Center
Ames Research Center (ARC)
Responsible NASA Representative
Ames Research Center LSDA Level 3
Project Manager: Helen Stewart
Institutional Support
National Aeronautics and Space Administration (NASA)
Alternate Experiment Name
C1514-5
Protocol / Approach
Hardware Items