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EXPERIMENT INFORMATION

Promoting Sensorimotor Response Generalizability (98-E120)
Principal Investigator
Research Area:
Neurophysiology
Species Studied
Scientific Name: Homo sapiens Species: Human

Description
OBJECTIVES:
The goal of this study is to develop an inflight treadmill training protocol that enhances adaptive generalization of locomotor function to facilitate rapid and robust recovery of functional mobility after long-duration space flight. Specifically, the investigator hopes to determine whether subjects exposed to a special inflight treadmill protocol will have greater proficiency in reassembling an appropriate, full-body postflight locomotor response. Will they recover locomotor function sooner than subjects not exposed to the inflight treadmill protocol? Data from this experiment are planned to be used to develop a countermeasure system.


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Publications
Miller CA, Feiveson AH, Bloomberg JJ. Effects of speed and visual-target distance on toe trajectory during the swing phase of treadmill walking. Journal of Applied Biomechanics, 2009 Feb;25(1):32-42.[pubmed.gov]

Mulavara AP, Feiveson AH, Fiedler J, Cohen H, Peters BT, Miller C, Brady R, Bloomberg JJ. Locomotor function after long-duration space flight: effects and motor learning during recovery. Exp Brain Res. 2010 Feb 5.[pubmed.gov]

Mulavara AP, Ruttley T, Cohen HS, Peters BT, Miller C, Brady R, Merkle L, Bloomberg JJ. Vestibular-somatosensory convergence in head movement control during locomotion after long-duration space flight. J Vestib Res. 2012 Jan 1;22(2):153-66.[pubmed.gov]

Keywords
Ataxia
Locomotion
Kinesthesis
Exercise
Mobility limitation

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Data Information
Data Availability
Archive is complete. Some data sets are online.
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Some data sets are not publicly available but can be requested.
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Parameters
Ataxia score
Body position
Eye movements
Kinematics
Long-term recovery parameter
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Mission/Study Information
Mission Launch/Start Date Landing/End Date Duration
Expedition 10 10/13/2004 04/24/2005 193 days
Expedition 11 04/14/2005 10/10/2005 179 days
Expedition 12 09/30/2005 04/30/2006 180 days
Expedition 5 06/05/2002 12/07/2002 185 days
Expedition 6 11/23/2002 05/03/2003 161 days
Expedition 7 04/25/2003 10/27/2003 185 days
Expedition 8 10/18/2003 04/29/2004 195 days
Expedition 9 04/18/2004 10/23/2004 188 days

Human Research Program (HRP) Human Research Roadmap (HRR) Information
Crew health and performance is critical to successful human exploration beyond low Earth orbit. The Human Research Program (HRP) investigates and mitigates the highest risks to human health and performance, providing essential countermeasures and technologies for human space exploration. Risks include physiological and performance effects from hazards such as radiation, altered gravity, and hostile environments, as well as unique challenges in medical support, human factors, and behavioral health support. The HRP utilizes an Integrated Research Plan (IRP) to identify the approach and research activities planned to address these risks, which are assigned to specific Elements within the program. The Human Research Roadmap is the web-based tool for communicating the IRP content.

The Human Research Roadmap is located at: https://humanresearchroadmap.nasa.gov/

+ Click here for information of how this experiment is contributing to the HRP's path for risk reduction.

Additional Information
Managing NASA Center
Johnson Space Center (JSC)
Responsible NASA Representative
Johnson Space Center LSDA Office
Project Manager: Pamela A. Bieri
Institutional Support
National Aeronautics and Space Administration (NASA)
Alternate Experiment Name
E120
MOBILITY
FMT
Functional Mobility
Proposal Date
05/01/2000
Proposal Source
98-HEDS-02