EXPERIMENT INFORMATION
Airway Nitric Oxide in Space (Airway_Monitoring)
Principal Investigator
Research Area:
Environmental monitoring
Environmental physiology
Hyper- and hypobaric physiology
Pulmonary physiology
Species Studied
Scientific Name: Homo sapiens Species: Human
Study Type
Description
OBJECTIVES:
The goal is to define how much the exhaled nitric oxide (NO) is reduced with combined microgravity and reduced ambient pressure, and by what mechanisms. This is considered very useful for the monitoring of lung health in future exploration-class space missions. Even more important, by manipulating the alveolar uptake of NO to the blood (increased in microgravity) and the speed of diffusion of NO in the respiratory zone of the lungs (by reduced ambient pressure) this study will be able to more precisely define the location of NO formation for the benefit of the diagnostic use of exhaled NO on the ground.
The goal is to define how much the exhaled nitric oxide (NO) is reduced with combined microgravity and reduced ambient pressure, and by what mechanisms. This is considered very useful for the monitoring of lung health in future exploration-class space missions. Even more important, by manipulating the alveolar uptake of NO to the blood (increased in microgravity) and the speed of diffusion of NO in the respiratory zone of the lungs (by reduced ambient pressure) this study will be able to more precisely define the location of NO formation for the benefit of the diagnostic use of exhaled NO on the ground.
Keywords
Respiratory Function Tests
Data Availability
Archiving in progress. Data is not yet available for this experiment.
Parameters
Air pressure, ambient
Airway pressure
Carbon dioxide, expired
Carbon dioxide, inspired
Humidity, ambient
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Mission/Study Information
| Mission | Launch/Start Date | Landing/End Date | Duration |
|---|---|---|---|
| Expedition 42 | 11/10/2014 | 03/11/2015 | 121 days |
| Expedition 43 | 03/11/2015 | 06/10/2015 | 91 days |
| Expedition 46 | 12/11/2015 | 03/02/2016 | 82 days |
| Expedition 47 | 03/02/2016 | 06/18/2016 | 108 days |
| Expedition 48 | 06/18/2016 | 09/06/2016 | 80 days |
| Expedition 49 | 09/06/2016 | 10/30/2016 | 54 days |
| Expedition 53 | 09/02/2017 | 12/14/2017 | 102 days |
| Expedition 54 | 12/14/2017 | 02/27/2018 | 75 days |
| Expedition 55 | 02/27/2018 | 06/03/2018 | 96 days |
| Expedition 56 | 06/03/2018 | 10/04/2018 | 123 days |
| Expedition 57 | 10/04/2018 | 12/20/2018 | 77 days |
| Expedition 58 | 12/18/2018 | 03/14/2019 | 85 days |
| Expedition 59 | 03/14/2019 | 06/24/2019 | 102 days |
Additional Information
Co-Investigators
Managing NASA Center
Johnson Space Center (JSC)
Responsible NASA Representative
Johnson Space Center LSDA Office
Project Manager: Eric Gallagher
Project Manager: Eric Gallagher
Institutional Support
European Space Agency (ESA)
Proposal Date
Proposal Source