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EXPERIMENT INFORMATION

Pulmonary Function and Evaluation During and Following Skylab Space Flights (SKYPUL)
Research Area:
Pulmonary physiology
Species Studied
Scientific Name: Homo sapiens Species: Human

Description
OBJECTIVES:
Research conducted during the Apollo Program showed no major changes in pulmonary function when evaluated by postflight exercise testing. Although pulmonary function has been studied in detail following exposure to hypoxic and hyperoxic environments, few studies have dealt with normoxic environments at reduced total pressure, as encountered during Skylab. The absence of a gravity vector would be expected to facilitate ventilation/perfusion relationships and result in better overall gas exchange in the weightless state.

Due to the absence in previous history of postflight pulmonary problems, and the normoxic microgravity environment of Skylab, vital capacity was initially proposed as the only functional screening. However, as a result of the magnitude of decreases in cardiac output following the first and second manned Skylab missions (Skylab 2 and 3), it was decided that more thorough pulmonary function screening was necessary for the final and longest duration Skylab mission (Skylab 4).


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Publications
Sawin CF, Nicogossian AE, Rummel JA, Michel EL. Pulmonary function evaluation during the Skylab and Apollo-Soyuz missions. Aviat Space Environ Med 1976; 47:168-172.[pubmed.gov]

Sawin CF, Nicogossian AE, Schachter AP, Rummel JA, Michel EL. Pulmonary Function Evaluation During and Following Skylab Space Flights. In: Johnston RS, Dietlein LF, editors. The Proceedings of the Skylab Life Sciences Symposium, Volume I; 1974 Aug 27-29; National Aeronautics and Space Administration, Johnson Space Center; 1974; 763-774. Report No: JSC-09275, Report No: TM X-58154. [NTRS]

Sawin CF, Nicogossian AE, Schachter AP, Rummel JA, Michel EL. Pulmonary Function Evaluation During and Following Skylab Space Flights. In: Johnston RS, Dietlein LF, eds. Biomedical Results from Skylab. Washington, DC: NASA Headquarters; 1977:388-394. NASA SP-377. [NTRS]

Sawin CF, Nicogossian AE, Schachter AP. Skylab 4 Pulmonary Function Testing. In: Skylab 4 Preliminary Biomedical Report. Houston TX: National Aeronautics and Space Administration; 1975. JSC Document Number 08818.

Keywords
Lung volume measurements
Pulmonary ventilation
Respiration
Respiratory Function Tests
Respiratory Mechanics

Data Information
Data Availability
Archive is complete. Data sets are not publicly available but can be requested.
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Parameters
Alveolar volume (V<sub>A</sub>)
CC/TLC ratio
Closing capacity (CC)
Closing volume (CV)
CV/VC ratio
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Mission/Study Information
Mission Launch/Start Date Landing/End Date Duration
Skylab 2 05/25/1973 06/22/1973 28 days
Skylab 3 07/28/1973 09/25/1973 59.5 days
Skylab 4 11/16/1973 02/08/1974 84 days

Additional Information
Managing NASA Center
Johnson Space Center (JSC)
Responsible NASA Representative
Johnson Space Center LSDA Office
Project Manager: Pamela A. Bieri
Institutional Support
National Aeronautics and Space Administration (NASA)
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