Ground Based Study: Campaign 19
Campaign 19 utilized 14 days of 6° head-down tilt bed rest, with 9 days of pre-bed rest and 7 days of recovery post best rest. This study followed the Flight Analogs Project (FAP) guidelines for subject recruitment, standard conditions of 6° head down tilt, and a set of standard measures collection. Standard measures represent a series of medical and research assessments to evaluate the human responses to bed rest under the 6° head down tilt. Vision measures were used to monitor subjects before, during, and after the 14 days of head-down tilt bed rest. This study consisted of the integration of standard measures, vision tests, and the investigator study protocol "Effects of Long- Duration Spaceflight on Venous and Arterial Compliance in Astronauts: Bed Rest Study.”
Campaign 19 testing was conducted on 12 male subjects and had one subject dismiss early with subjects divided between two age groups (25-35 years and 45-55 years) who underwent 14 days of 6º head-down tilt bed rest. Sodium intake was comparable to the reported in-flight sodium intake of astronauts, rather than the lower sodium level ingested under the standard bed rest diet. In this study, the impact of age and sodium intake on the development of the VIIP syndrome were assessed.