Astronauts Schweickart and Scott performed a spacewalk, and Schweickart checked out the new Apollo spacesuit, the first to have its own life support system rather than being dependent on an umbilical connection to the spacecraft. Apollo 9 gave proof that the Apollo spacecraft was up to the task of orbital rendezvous and docking. The performance of both the spacecraft and its subsystems was nearly flawless, and all mission objectives were met. The Apollo 9 mission qualified the launch vehicle, the lunar landing spacecraft, the portable life support system backpack and the flight control techniques designed for manned lunar landing flights.
Crew operations left little opportunity for inflight science, similar to the preceding Apollo missions. However, before and after flight, researchers studied several physiological systems. Investigators evaluated the crewmembers' cardiovascular response to exercise pre- and post flight, using a bicycle ergometer and other exercise equipment, and studied the response of the cardiovascular system to weightlessness using lower body negative pressure and passive stand tests.
The clinical aspects of crew health and safety were investigated by performing medical examinations and conducting inflight medical monitoring as evaluation methods. Investigators also studied musculoskeletal changes, clinical disorders in space due to imbalance between bone formation and resorption, inflight weight loss and inflight caloric intake. Another important aspect of crew health and safety is the protection against radiation, so one experiment focused on analyzing natural and man-made radiation encountered in space, with the goal of finding ways of limiting the astronauts' exposure to radiation. Vestibular system experiments not only aided researchers in gaining a better understanding of the mechanisms that provide balance and coordination, but also contributed to alleviating the symptoms of space adaptation syndrome.
The endocrinology experiments sought to understand biochemical changes in crewmembers by studying the balance of fluids and electrolytes, regulation of calcium metabolism and the adaptation of metabolic processes to the space environment.
Scientists also utilized specific laboratory data to assess the health status of the astronauts prior to their commitment to space flight. This allowed them to detect and identify any alterations in the normal functions of the immunological and hematological systems which could be attributed to space flight exposure and to evaluate the significance of these changes relative to a person's continuing participation in space flight missions. Biochemistry data, when integrated with the data obtained from a complete history and physical examination of each crewmember, permitted an objective assessment of crew physical status.
The detection of potentially pathogenic microorganisms was attempted, so that associated medical problems could be identified early and preventive measures could be established. These objectives included the identification of medically important microorganisms recovered from ill crew members to aid in diagnosis and treatment.